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Dendritic Macromolecules as Inhibitors to Protein-Protein Binding
Authors:Fumiko Chiba  Ting Chou Hu  Lance J Twyman  Mark Wagstaff
Institution:Department of Chemistry, Sheffield University, Brook Hill, Sheffield, S2 7HF, UK
Abstract:Summary: Our initial studies into protein binding using a series of dendrimers as size selective inhibitors have been described. Two different proteins, cytochromo-c and chymotrypsin have been selected for these binding experiments.
Keywords:chymotripysin  cytochrome-c  dendrimers  protein-protein interactions
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