Biologically active constituents of Arnebia euchroma: structure of arnebinol, an ansa-type monoterpenylbenzenoid with inhibitory activity on prostaglandin biosynthesis. |
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| Authors: | X S Yao Y Ebizuka H Noguchi F Kiuchi M Shibuya Y Iitaka H Seto U Sankawa |
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| Affiliation: | Faculty of Pharmaceutical Sciences, University of Tokyo, Japan. |
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| Abstract: | Three phenolic compounds were isolated from the roots of Arnebia euchroma as inhibitors of in vitro prostaglandin biosynthesis. Two known compounds were identified as shikonofurans and des-O-methyllasiodiplodin. The other new compound was named arnebinol and its structure was elucidated as a novel ansa-type monoterpenylbenzenoid derivative. |
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