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A concise asymmetric synthesis of (-)-rasfonin |
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| Authors: | Huang Yange Minnaard Adriaan J Feringa Ben L |
| Affiliation: | Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands. |
| Abstract: | A very efficient total synthesis of the apoptosis inducer (-)-rasfonin has been developed using CuBr/JosiPhos catalyzed iterative asymmetric conjugate addition of MeMgBr and Feringa's butenolide. |
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