Communicating chemical congregation: a molecular AND logic gate with three chemical inputs as a "lab-on-a-molecule" prototype |
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| Authors: | Magri David C Brown Gareth J McClean Gareth D de Silva A Prasanna |
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| Affiliation: | School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, Northern Ireland. d.magri@qub.ac.uk |
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| Abstract: | We demonstrate the first three-input molecular AND logic gate based on three chemical inputs as a direct way of detecting congregations of chemical species. The AND gate operates in water and responds to Na+, H+, and Zn2+ inputs with an enhanced fluorescence signal when pre-set concentration thresholds are exceeded. Future "lab-on-a-molecule" devices could have application in medicine for rapid disease screening. |
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