A chromatographic method for detection of end points in chemical reactions

Summary Gas chromatography is recognized as an analytical technique possessing desirable advantages for a wide range of applications. The purpose of this work is to demonstrate the usefulness of GC instrumentation for determining values of end-points for a variety of reactions. Gas chromatographic titrimetry may be characterized as that in which the change of peak-height ratio of the reaction during a titration is recorded as a function of titrant added. The experimental data are fitted to simple first-order interpolation equations, so that the titration curve, when extrapolated, intersects the volume axis, the point of intersection being the equivalence-point volume. The end-point values are in good agreement with those reported in the literature and with control measurements. From the results it is concluded that the method can be used with high confidence to determine end-point values in a fast and easy way.