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A Metal–Organic Framework/DNA Hybrid System as a Novel Fluorescent Biosensor for Mercury(II) Ion Detection
Authors:Lan‐Lan Wu  Zhuo Wang  Shu‐Na Zhao  Xing Meng  Xue‐Zhi Song  Prof Jing Feng  Prof Shu‐Yan Song  Prof Hong‐Jie Zhang
Institution:1. State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China);2. University of Chinese Academy of Sciences, Beijing, 100049 (P. R. China);3. School of Petroleum and Chemical Engineering, Dalian University of Technology, 2 Dagong Road, Liaodongwan New District, Panjin 124221, Liaoning (P. R. China)
Abstract:Mercury(II) ions have emerged as a widespread environmental hazard in recent decades. Despite different kinds of detection methods reported to sense Hg2+, it still remains a challenging task to develop new sensing molecules to replenish the fluorescence‐based apparatus for Hg2+ detection. This communication demonstrates a novel fluorescent sensor using UiO‐66‐NH2 and a T‐rich FAM‐labeled ssDNA as a hybrid system to detect Hg2+ sensitively and selectively. To the best of our knowledge, it has rarely been reported that a MOF is utilized as the biosensing platform for Hg2+ assay.
Keywords:DNA  fluorescence  host–  guest systems  mercury  metal–  organic frameworks
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