Synthesis,Crystal Structure and Biological Activities of Novel Anthranilic(Isophthalic) Acid Esters |
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Authors: | YAN Tao YU Guan-ping LIU Peng-fei XIONG Li-xia YU Shu-jing LI Zheng-ming |
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Institution: | State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China |
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Abstract: | In search of environmentally benign insecticides with high activity, low toxicity and low resistance, a series of novel anthranilic(isophthalic) acid esters was designed and synthesized based on the structure of ryanodine modulating agent. All the compounds were characterized by 1H NMR spectra, elemental analysis or high resolution mass spectrometry(HRMS). The preliminary results of biological activity assessment indicate that some of the title compounds exhibit certain but unremarkable insecticidal activity against Mythimna separata Walker at 200 mg/L and fungicidal activities against five funguses at 50 mg/L. |
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Keywords: | Anthranilic acid Isophthalic acid Crystal structure Biological activity |
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