| Divergent pathways of β,γ-unsaturated α-diazocarbonyl compounds catalyzed by dirhodium and Lewis acids catalysts separately or in combination |
| |
| 引用本文： | Xin-Fang Xu,Michael P.Doyle. Divergent pathways of β,γ-unsaturated α-diazocarbonyl compounds catalyzed by dirhodium and Lewis acids catalysts separately or in combination[J]. 中国化学快报, 2015, 26(2): 227-232. DOI: 10.1016/j.cclet.2014.12.014 |
| |
| 作者姓名： | Xin-Fang Xu Michael P.Doyle |
| |
| 作者单位： | a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Dushu Lake Campus, Soochow University, Suzhou 215123, China;b Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA |
| |
| 基金项目： | MPD is grateful to the National Institutes of Health (No. GM 46503) and the National Science Foundation (No. CHE-1212446). XFX is thankful to the starting funding from Soochow University and Key Laboratory of Organic Synthesis of Jiangsu Province. |
| |
| 摘 要： | β,γ-Unsaturated a-diazocarbonyl compounds possess two reactive sites for electrophilic addition-one at the diazo carbon and the other at the vinylogous γ-position.Controlled by catalyst,divergent transformations are achieved starting from the same starting materials,either by Lewis acid-catalyzed addition or by dirhodium-catalyzed metal carbene reactions.In select cases two catalysts working in combination or in sequence provide a relay for cascade transformations.In this review,we summarize advances in catalyst-dependent divergent transformations of β,γ-unsaturated α-diazocarbonyl compounds and highlight the potential of this exciting research area and the many challenges that remain.
|
| 关 键 词： | Divergent synthesis β,γ-Unsaturated α-diazocarbonyl compounds Metal carbene(carbenoid) Dirhodium Lewis acid catalyst |
| 收稿时间： | 2014-11-13 |
| 修稿时间： | 2014-12-11 |
Divergent pathways of β,γ-unsaturated α-diazocarbonyl compounds catalyzed by dirhodium and Lewis acids catalysts separately or in combination |
| |
| Xin-Fang Xu,Michael P. Doyle. Divergent pathways of β,γ-unsaturated α-diazocarbonyl compounds catalyzed by dirhodium and Lewis acids catalysts separately or in combination[J]. Chinese Chemical Letters, 2015, 26(2): 227-232. DOI: 10.1016/j.cclet.2014.12.014 |
| |
| Authors: | Xin-Fang Xu Michael P. Doyle |
| |
| Affiliation: | a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Dushu Lake Campus, Soochow University, Suzhou 215123, China;b Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA |
| |
| Abstract: | β,γ-Unsaturated α-diazocarbonyl compounds possess two reactive sites for electrophilic addition -one at the diazo carbon and the other at the vinylogous g-position. Controlled by catalyst, divergent transformations are achieved starting from the same starting materials, either by Lewis acid-catalyzed addition or by dirhodium-catalyzed metal carbene reactions. In select cases two catalysts working in combination or in sequence provide a relay for cascade transformations. In this review, we summarize advances in catalyst-dependent divergent transformations of β,γ-unsaturated α-diazocarbonyl compounds and highlight the potential of this exciting research area and the many challenges that remain. |
| |
| Keywords: | Divergent synthesis &beta ,&gamma -Unsaturated &alpha -diazocarbonyl compounds Metal carbene (carbenoid) Dirhodium Lewis acid catalyst |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国化学快报》浏览原始摘要信息 |
|
点击此处可从《中国化学快报》下载全文 |
|
