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Copper-catalyzed amide bond formation from formamides and carboxylic acids |
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| Authors: | Hong-Qiang Liu Jun Liu Yang-Hui Zhang Chang-Dong Shao Jing-Xun Yu |
| Affiliation: | a Department of Chemistry, Tongji University, Shanghai 200092, China;b Key Laboratory of Yangtze River Water Environment, Ministry of Education, Tongji University, Shanghai 200092, China |
| Abstract: | A highly efficient copper-catalyzed approach to form amide bonds from formamides and carboxylic acids was developed. This protocol shows broad substrate scopes and high yields in the presence of 1 mol% catalyst and 4.0 equiv. formamides. |
| Keywords: | Amides Formamides Carboxylic acids Copper Catalysis |
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