Efficient, intermolecular, oxidative radical alkylation of heteroaromatic systems under "tin-free" conditions |
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| Authors: | Osornio Yazmin M Cruz-Almanza Raymundo Jiménez-Montaño Vicente Miranda Luis D |
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| Institution: | Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior S. N., Ciudad Universitaria, Coyoacán, México, DF 04510, México. |
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| Abstract: | Novel and efficient radical alkylation of several heterocyclic systems including pyrroles, indoles, furan and thiophenes is described using xanthate based radical chemistry. The present methodology could be used to provide rapid access to various nonsteroidal antiinflammatory drugs. |
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