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Conjugation of poor inhibitors with surface binding groups: a strategy to improve inhibition |
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| Authors: | Roy Bidhan C Hegge Ryan Rosendahl Theresa Jia Xiao Lareau Rachael Mallik Sanku Srivastava D K |
| Institution: | Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, North Dakota, USA. |
| Abstract: | Conjugation of surface binding groups with inhibitors for carbonic anhydrase leads to the conversion of weak inhibitors to strong inhibitors. |
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