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Conjugation of poor inhibitors with surface binding groups: a strategy to improve inhibition
Authors:Roy Bidhan C  Hegge Ryan  Rosendahl Theresa  Jia Xiao  Lareau Rachael  Mallik Sanku  Srivastava D K
Institution:Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, North Dakota, USA.
Abstract:Conjugation of surface binding groups with inhibitors for carbonic anhydrase leads to the conversion of weak inhibitors to strong inhibitors.
Keywords:
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