Nicotine-based ionic liquid supported on magnetic nanoparticles: An efficient and recyclable catalyst for selective one-pot synthesis of mono- and bis-4H-pyrimido[2,1-b]benzothiazoles |
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Authors: | Nasrin Alishahi Mahboobeh Nasr-Esfahani Iraj Mohammadpoor-Baltork Shahram Tangestaninejad Valiollah Mirkhani Majid Moghadam |
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Affiliation: | Department of Chemistry, Catalysis Division, University of Isfahan, Isfahan, 81746-73441 Iran |
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Abstract: | In this study, an acidic nicotine-based ionic liquid supported on magnetic nanoparticles ([NicTC]HSO4@MNPs) was synthesized and characterized by different techniques. The activity of this catalyst was evaluated in a multi-component reaction of 2-aminobenzothiazole , aldehydes / dialdehydes and β-ketoesters/1,3-diketones to afford a series of novel mono- and bis-4H-pyrimido[2,1-b]benzothiazole derivatives. In addition, mild reaction conditions, high yields, excellent selectivity as well as easy recovery and reusability of the catalyst, make this method an economic and environmentally-benign process. |
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Keywords: | 4H -Pyrimido[2,1-b]benzothiazoles fused heterocyclic compounds nicotine-based ionic liquid selective synthesis solvent-free conditions |
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