Hierarchical Self-Assembled Photo-Responsive Tubisomes from a Cyclic Peptide-Bridged Amphiphilic Block Copolymer |
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| Authors: | Dr Jie Yang Ji-Inn Song Dr Qiao Song Julia Y Rho Dr Edward D H Mansfield Stephen C L Hall Megan Sambrook Prof Feihe Huang Prof Sébastien Perrier |
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| Institution: | 1. Department of Chemistry, University of Warwick, Coventry, CV4 7AL UK;2. Department of Chemistry, Zhejiang University, Hangzhou, 310027 China |
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| Abstract: | Typically, the morphologies of the self-assembled nanostructures from block copolymers are limited to spherical micelles, wormlike micelles and vesicles. Now, a new generation of materials with unique shape and structures, cylindrical soft matter particles (tubisomes), are obtained from the hierarchical self-assembly of cyclic peptide-bridged amphiphilic diblock copolymers. The capacity of obtained photo-responsive tubisomes as potential drug carriers is evaluated. The supramolecular tubisomes pave an alternative way for fabricating polymeric tubular structures, and will expand the toolbox for the rational design of functional hierarchical nanostructures. |
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| Keywords: | Wirkstoffbeladung Nanoröhren Peptid-Polymer-Konjugate Photoresponsive Materialien Tubisomen |
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