Copper coordinated-poly(α-amino acid) decorated on magnetite graphene oxide as an efficient heterogeneous magnetically recoverable catalyst for the selective synthesis of 5- and 1-substituted tetrazoles from various sources: A comparative study |
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| Authors: | Milad Kazemnejadi Boshra Mahmoudi Zeinab Sharafi Mohammad A Nasseri Ali Allahresani Mohsen Esmaeilpour |
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| Institution: | 1. Department of Chemistry, Faculty of Sciences, University of Birjand, Birjand, Iran;2. Research Center, Sulaimani Polytechnic University, Sulaimani, Iraq;3. Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran;4. Department of Chemistry, College of Science, Shiraz University, Shiraz, Iran |
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| Abstract: | In this work, poly(α-amino acid)-Cu(II) complex immobilized on magnetite graphene oxide (GO/Fe3O4@PAA-Cu-complex) was prepared via a multistep synthesis and employed as an efficient, heterogeneous, magnetically recyclable nanocatalyst for one-pot, three component synthesis of 5- and 1-substituted tetrazoles using different substrates including benzaldehydes, benzonitriles, and anilines in mild conditions. The different approaches were mechanically investigated and compared. The catalyst was fully characterized by Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), vibrating sample magnetometer (VSM), energy dispersive X-ray spectroscopy (EDX), inductively coupled plasma (ICP), FE-SEM and TEM analyses. The magnetic nanocatalyst could be readily separated from the reaction mixture by an external magnet and reused for several times without significant loss of catalytic activity. Also, the spectroscopic analysis revealed the stability and durability of the catalyst. Finally, the chemoselectivity of the method was investigated by the various combinations of aldehyde, nitrile, and oxime. |
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| Keywords: | copper complex graphene oxide poly(α-amino acid) 5-substituted 1H-tetrazole 1-substituted-1H-1 2 3 4-tetrazoles |
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