Palladium-catalyzed cross-coupling reactions of coumarin derivatives: An overview |
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Authors: | U.S. Kanchana Elizabeth J. Diana Thomas V. Mathew Gopinathan Anilkumar |
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Affiliation: | 1. Department of Chemistry, St. Thomas College Pala, Arunapuram P.O., Kottayam, Kerala, 686574 India;2. School of Chemical Sciences, Mahatma Gandhi University, P D Hills PO, Kottayam, Kerala, 686560 India |
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Abstract: | Coumarins are omnipresent in several plants and exhibit a plethora of pharmacological properties, making them an important scaffold in organic synthesis. Naturally, the chemistry of this motif has attracted ever-increasing attention, among which palladium-catalyzed coupling reactions are the most prevalent one. Numerous useful, easy, and concise syntheses and reactions have been achieved using palladium-catalyzed coupling reactions. This review focuses on recent advances in palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, Stille, Sonogoshira etc. reactions of coumarin derivatives and covers the literature from 2001 to 2020. |
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Keywords: | catalysis C–C coumarin cross-coupling palladium |
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