Copper-immobilized ionic liquid as an alternative to organic solvents in the one-pot synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives |
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| Authors: | Hossein Ghafuri Maede Kazemnezhad Leili Hamid Reza Esmaili Zand |
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| Affiliation: | Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, P.O. Box 16846-13114, Tehran, I.R. Iran |
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| Abstract: | In this study, a novel Cu-immobilized ionic liquid (IL)was designed, characterized, and employed as both promoter and solvent in the synthesis of some dihydropyrano[2,3-c]pyrazoles. The synthesized ionic liquid was characterized by 1H NMR, 13C NMR, FTIR, ICP and EDX analysis and showed high catalytic activity to proceed the synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives. This method has the advantage of using the IL as a green medium for the synthesize of the products in high to excellent yields within short reaction times. |
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| Keywords: | Condensation Copper Dihydropyrano pyrazole Ionic liquid |
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