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Novel marine-based gold nanocatalyst in solvent-free synthesis of polyhydroquinoline derivatives: Green and sustainable protocol |
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| Authors: | Mahsa Sepahvand Foad Buazar Mohammad Hosein Sayahi |
| Affiliation: | 1. Department of Marine Chemistry, Khorramshahr University of Marine Science and Technology, PO Box 669, Khorramshahr, Iran;2. Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran Contribution: Formal analysis, Methodology, Project administration, Validation |
| Abstract: | We report an ecofriendly synthetic approach for the fabrication of biogenic gold nanoparticles (AuNPs) using electron-rich sea cucumber extract as a bio-reductant and stabilizing agent in reducing gold cations into AuNPs at the optimal conditions. The produced AuNPs are spherical in shape with an average particle size of 11 ± 1.5 nm in transmission electron microscopy (TEM) and exhibited a crystal structure of face-centered cubic in X-ray diffraction (XRD) analyses. Our results indicated that bioinspired AuNPs demonstrate superior catalytic activity in the safe and facile one-pot synthesis of polyhydroquinoline derivatives under solvent-free reaction conditions. This green route encompasses multiple benefits including highly recyclable bioinspired catalyst (5 cycles), short reaction times, convenient workout, high to excellent product yields (82%–97%), and nonhazardous conditions. |
| Keywords: | biosynthesis gold nanocatalyst polyhydroquinoline sea cucumber extract |