Recent developments in the utility of Zn(L-proline)2 as benign and recyclable metallo-organocatalyst in organic synthesis |
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| Authors: | Kamal Usef Sadek Ramadan Ahmed Mekheimer Mohamed Abd-Elmonem Mohamed Hilmy Elnagdi |
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| Affiliation: | 1. Chemistry Department, Faculty of Science, Minia University, Minia, 61519 Egypt;2. Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt |
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| Abstract: | The coordination of Zn (II) with L - proline as a choral ligand makes the initiated complex Zn(L-proline)2 a moderately soft Lewis acid. Recently Zn(L-proline)2 has emerged as a promising reusable chiral catalyst which could be utilized in a diversity of transformations. The present short review article focuses mainly on recent developments in utility of Zn(L-proline)2 in organic synthesis. This includes Aldol condensation, synthesis of heterocyclic compounds with five, six and fused rings. |
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| Keywords: | Aldol reaction five and six membered rings fused heterocycles Metallo-organocatalysts Zn(L-proline)2 |
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