Interfacial Microcompartmentalization by Kinetic Control of Selective Interfacial Accumulation |
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| Authors: | Dr Qian Liu Dr Zhenyu Yuan Dr Meng Zhao Max Huisman Gido Drewes Dr Tomasz Piskorz Dr Serhii Mytnyk Dr Ger J M Koper Dr Eduardo Mendes Prof Dr Jan H van Esch |
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| Institution: | 1. Department of Chemical Engineering, Delft University of Technology, van der Maasweg 9, Delft, 2629 HZ The Netherlands;2. Department of Chemical Engineering, East China University of Science and Technology, Meilong 130, Shanghai, 200237 P. R. China;3. Department of Materials Science and Engineering, Delft University of Technology, Mekelweg 2, Delft, 2628 CD The Netherlands |
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| Abstract: | Reported here is a 2D, interfacial microcompartmentalization strategy governed by 3D phase separation. In aqueous polyethylene glycol (PEG) solutions doped with biotinylated polymers, the polymers spontaneously accumulate in the interfacial layer between the oil-surfactant-water interface and the adjacent polymer phase. In aqueous two-phase systems, these polymers first accumulated in the interfacial layer separating two polymer solutions and then selectively migrated to the oil-PEG interfacial layer. By using polymers with varying photopolymerizable groups and crosslinking rates, kinetic control and capture of spatial organisation in a variety of compartmentalized macroscopic structures, without the need of creating barrier layers, was achieved. This selective interfacial accumulation provides an extension of 3D phase separation towards synthetic compartmentalization, and is also relevant for understanding intracellular organisation. |
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| Keywords: | interfaces kinetics microparticles photochemistry polymers |
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