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Analysis of the effect of malaria on lipid composition of rhesus plasma
Authors:S McClean  A Kabat  J Sampugna  WC purdy  G McCormick
Institution:Department of Chemistry, University o f Maryland, College Park. Maryland 20742 U.S.A.;Department of Endocrinology and Metabolism, Division of Medicine, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C. 20012 U.S.A.
Abstract:The phospholipid distribution and the ratio of cholesterol-to-cholesterol ester have been determined for plasmas isolated from normal, fasted and P. knowlesi-infected rhesus monkeys. Compared to normal plasmas, the infected plasmas show phospholipid patterns with slight increases in phosphatidylcholine and larger decreases in lysophosphatidylcholine. The cholesterol-to-cholesterol ester ratio is always less than one in normal plasmas and greater than one for infected plasmas. There are no differences between samples isolated from fasting and non-fasting animals for any of the constituents examined.
Keywords:Present address: Clinical Center  National Institutes of Health  Bethesda  Maryland 20014  
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