Analysis of the effect of malaria on lipid composition of rhesus plasma |
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Authors: | S McClean A Kabat J Sampugna WC purdy G McCormick |
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Institution: | Department of Chemistry, University o f Maryland, College Park. Maryland 20742 U.S.A.;Department of Endocrinology and Metabolism, Division of Medicine, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C. 20012 U.S.A. |
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Abstract: | The phospholipid distribution and the ratio of cholesterol-to-cholesterol ester have been determined for plasmas isolated from normal, fasted and P. knowlesi-infected rhesus monkeys. Compared to normal plasmas, the infected plasmas show phospholipid patterns with slight increases in phosphatidylcholine and larger decreases in lysophosphatidylcholine. The cholesterol-to-cholesterol ester ratio is always less than one in normal plasmas and greater than one for infected plasmas. There are no differences between samples isolated from fasting and non-fasting animals for any of the constituents examined. |
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Keywords: | Present address: Clinical Center National Institutes of Health Bethesda Maryland 20014 |
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