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Synthesis and Application of a Full Water‐Soluble and Red‐Emitting Chemosensor Based on Phenoxazinium for Copper(II) Ions |
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| Authors: | Baolong Yan Ru Sun Jianfeng Ge Yujie Xu Qianqian Zhang Xuebo Yang Jianmei Lu |
| Affiliation: | 1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Material Science, Soochow University, Suzhou, Jiangsu 215123, China;2. School of Radiation Medicine and Protection, Medicine College of Soochow University, Suzhou, Jiangsu 215123, China;3. Key Laboratory of Functional Materials for Environment Protection of Suzhou City, Soochow University, Suzhou, Jiangsu 215123, China |
| Abstract: | A phenoxazinium‐based chemosensor ( 1 ) bearing di(2‐picolyl)amine unit was successfully synthesized. The result shows that it is a red‐emitting and full water‐soluble chemosensor for the selective detection of Cu2+ in pure water. The fluorescence on‐off mechanism was studied by ab initio calculations. To confirm the suitability of 1 for biological applications, it was employed in the fluorescence detection of the intracellular Cu2+ with cultured KB cells. The results indicated that 1 had good membrane permeability and could be useful for the fluorescence microscopic imaging. |
| Keywords: | chemosensor phenoxazinium water‐soluble copper |