Studies toward the Synthesis of (R)‐(+)‐Harmicine |
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| Authors: | Fanyang Mo Fei Li Di Qiu Yan Zhang Jianbo Wang |
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| Affiliation: | Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China |
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| Abstract: | The study toward the total synthesis of (R)‐(+)‐harmicine is reported in this paper. The enantioselective synthesis of pyrrolidinone, the main backbone of of (R)‐(+)‐harmicine, has been completed by the methodology based on photo‐induced Wolff rearrangement of α‐diazo‐β‐carbonyl compounds. |
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| Keywords: | diastereoselective synthesis (R)‐(+)‐harmicine diazo compounds Wolff rearrangement photo‐induced reaction |
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