Terpenoids from a Chinese Gorgonian Anthogorgia sp. and Their Antifouling Activities |
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Authors: | Dawei Chen Dong Liu Shi Shen Wei Cheng Wenhan Lin |
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Affiliation: | State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China |
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Abstract: | Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane‐type diterpenoid anthogorgiene P ( 1 ) and a guaiazuene‐based terpenoid anthogorgiene Q ( 2 ). Anthogorgiene P ( 1 ) contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods (IR, UV, MS, CD and NMR). Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition. |
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Keywords: | marine gorgonian Anthogorgia sp. terpenoids anthogorgienes P– Q structural elucidation antifouling activity |
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