Rasta Resin–PPh3–NBniPr2 and its Use in One‐Pot Wittig Reaction Cascades |
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Authors: | Yan Teng Jinni Lu Prof. Dr. Patrick H. Toy |
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Affiliation: | Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P. R. of China), Fax: (+852)?2857‐1586 |
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Abstract: | A new triarylphosphine–tertiary amine bifunctional polymeric reagent has been prepared and used effectively in a variety of one‐pot Wittig reactions. The design of this reagent resolved a deficiency of a previously reported related material, and allowed it to perform more efficiently in such reactions. Furthermore, it was readily recyclable, and was also successfully applied in cascade processes involving one‐pot Wittig reactions followed by either a conjugate reduction or a reductive aldol reaction. In these reaction cascades, the phosphine oxide groups generated in the Wittig reaction served as the catalyst for the subsequent reaction. |
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Keywords: | aldol reaction conjugate reduction reaction immobilization polymer‐supported reagent Wittig reactions |
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