Copper Supported on the SiO2 Nanoparticle in Click Chemistry: An Alternative Catalytic System for Regioselective and One‐Pot Synthesis of 1,2,3‐Triazoles and β‐Hydroxytriazoles |
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| Authors: | Maryam Ciyabi Hashjin Roghayeh Ciyabi Maryam Baharloui Ghaffar Hosseini Hamed Tavakoli |
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| Affiliation: | Department of Chemistry, Faculty of Science, Islamic Azad University, Karaj Branch, P.O. Box 31485‐313, Karaj, Iran |
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| Abstract: | In this work, readily prepared copper supported on the SiO2 nanoparticles has been found to effectively catalyze the 1,3‐dipolar cycloaddition of a variety of azides, alkynes, epoxides and sodium azide, furnishing the corresponding 1,2,3‐triazoles and β‐hydroxytriazoles. Click reaction proceeds in short reaction times and under mild reaction conditions, and the resulting products are obtained in good yields at ambient temperature. |
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| Keywords: | nanoparticle 1 3‐dipolar cycloaddition 1 2 3‐triazole β ‐hydroxytriazole |
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