New alkylamide from the stems of Zanthoxylum nitidum |
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| Authors: | Suda Chakthong Rangsima Ampaprom Sakawduen Inparn Uraiwan Phetkul Sasitorn Chusri Surasak Limsuwan |
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| Affiliation: | 1. Faculty of Science, Department of Chemistry, Prince of Songkla University, Hat Yai, Songkhla, Thailand;2. Natural Product Research Center of Excellence, Prince of Songkla University, Hat Yai, Songkhla, Thailand;3. Natural Product Research Center of Excellence, Prince of Songkla University, Hat Yai, Songkhla, Thailand;4. Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand |
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| Abstract: | A new alkylamide, named (2E,6E,8E)-N-(2-methylpropyl)-10-oxo-2,6,8-decatrienamide (1), together with 22 known compounds (2–23), were isolated from the stems of Zanthoxylum nitidum. Their structures were elucidated by spectroscopic methods, including 1D and 2D NMR spectroscopy. The isolated compounds exhibited slightly antioxidant activities through DPPH and ABTS radical scavenging assays but showed no antibacterial activity against Streptococcus mutans ATCC2517, a dental caries causing bacteria. |
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| Keywords: | Zanthoxylum nitidum alkylamide Rutaceae antioxidant antibacterial |
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