A new norisoprenoid from the leaves of Ficus pumila |
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Authors: | Meng Bai Yue Cai Shou-Yuan Wu Xiao-Ping Song Guang-Ying Chen |
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Institution: | 1. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou, China;2. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou, China;3. Hainan Institute of Science and Technology , Haikou, P.R. China |
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Abstract: | One new norisoprenoid 3,9-dihydroxy dihydro actinidiolide (1), together with eleven known compounds (2–12), were isolated from ethanol extract of the leaves of Ficus pumila collected in Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds 1, 2, 4, 5, 8 and 10–12 were isolated from the F. pumila for the first time. All compounds were evaluated for their cytotoxic activity. Compounds 3 and 9 showed weak cytotoxic activity against Hela, MCF-7 and A549 cell lines. |
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Keywords: | Ficus pumila chemical constituents cytotoxic activity |
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