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Laceioside,a new cycloartane saponin from Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.
Authors:Viqar Uddin Ahmad  Faryal Vali Mohammad  Rasool Bakhsh Tareen
Affiliation:1. H.E.J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan;2. Department of Botany, Baluchistan University, Quetta, Pakistan
Abstract:Phytochemical investigation of the aerial parts of Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff. (Family Fabaceae) resulted in the isolation of a new cycloartane glycoside laceioside (1). The structure of the previously undescribed compound 1 was established as 16β-acetyloxy-3-O-β-d-glucopyranosyloxy-cycloartan-11α,24ξ, 25-triol. The structure elucidation of compound 1 was based primarily on 1D and 2D-NMR techniques including 1H and 13CNMR spectra, DEPT and by 2D COSY, HSQC and HMBC experiments.
Keywords:Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.  Fabaceae  cycloartane triterpenoid glycoside
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