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One new Lignan derivative from the fruiting bodies of Ganoderma lipsiense
Authors:Meng Bai  Shou-Yuan Wu  Wen-Fei Zhang  Xiao-Ping Song  Chang-Ri Han
Affiliation:1. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China;2. Ministry of Education Key Laboratory for Ecology of Tropical Islands, College of Life Sciences, Hainan Normal University, Haikou 571158, China;3. Hainan Institute of Science and Technology, Haikou 571126, China
Abstract:One new lignan derivative 2,3-dimethyl-4-(4′-hydroxy-3′,5′-dimethoxyphenyl)-6-hydroxy-7-methoxy-naphthalene (1), together with four known analogues (2-5), were isolated from acetone extract of the fruiting bodies of Ganoderma lipsiense collected in the Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 1 showed insecticidal activity against newly hatched karvae of Helicoverpa armigera Hubner. Compounds 1-5 showed moderate antibacterial activity against Staphylococcus aureus with the same MIC value of 1.25?μg/mL.
Keywords:Ganoderma lipsiense  chemical constituents  biological activity
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