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A new dimeric secoiridoids derivative,japonicaside E,from the flower buds of Lonicera japonica
Authors:Wen Ge  Hai-Bo Li  Hui Fang  Biao Yang  Wen-Zhe Huang
Institution:1. Nanjing University of Chinese Medicine, Nanjing, China;2. Jiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;3. State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, China;4. Jiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China
Abstract:A new dimeric secoiridoids derivative, named japonicaside E, together with six known compounds were isolated from the flower buds of Lonicera japonica. The structures of these compounds were elucidated by the analyses of mass spectrometry and NMR spectroscopy. All compounds were evaluated for anti-inflammatory activity in vitro.
Keywords:Lonicera japonica  japonicaside E  dimeric secoiridoids glucoside  anti-inflammatory  PGE2
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