A new benzofuran from the heartwood of Dalbergia latifolia |
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Authors: | Rong-Hua Liu Dan-Yi Mei Shuai Lin Ding-Qing Wang Lan-Ying Chen |
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Institution: | Key Laboratory of Innovation Drug and Efficient Energy-Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang, China |
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Abstract: | A new benzofuran compound, named 2-5-hydroxy-4-methoxy-2-(3-p-henyl-trans-allyloxy)benzyl]-5-hydroxy-6-methoxy-3-phenylbenzofuran (1), together with (+)-obtusafuran (2) and isoparvifuran (3), was isolated from the heartwood of Dalbergia latifolia. Their structures were elucidated by a combination of spectroscopic methods and comparison with the literature. Compounds 2 and 3 were obtained from this plant for the first time. Compound 1 exhibited moderated antioxidant effect for scavenging 1,1-diphenyl-2-picryhydrazyl (DPPH) free radical (IC50 = 96.7 ± 8.9 μM). |
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Keywords: | Dalbergia latifolia benzofuran antioxidant activity 2-[5-hydroxy-4-methoxy-2-(3-phenyl-trans-allyloxy)benzyl]-5-hydroxy-6-methoxy-3-phenylbenzofuran |
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