Three new biflavonoids from the branches and leaves of Cephalotaxus oliveri and their antioxidant activity |
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| Authors: | Shu Xiao Zhen-Qiang Mu |
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| Affiliation: | 1. School of Chemical Engineering, Institute of Pharmaceutical Engineering Technology and Application, Key Laboratory of Green Chemistry of Sichuan Institutes of Higher Education, Sichuan University of Science &2. Engineering, Zigong, People’s Republic of China |
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| Abstract: | Three new biflavonoids, named oliveriflavones A-C (1–3), together with two known flavonoids (quercetin (4) and rutin (5)), were isolated from the endangered plant Cephalotaxus oliveri. The chemical structures of these compounds were elucidated by comprehensive spectroscopic methods including NMR, HRESIMS, IR, UV, and CD spectra. Compounds 1–5 were first isolated from the genus Cephalotaxus. All the compounds were tested for their antioxidant activity. Compounds 4 and 5 showed excellent activity with IC50 values of 0.03 ± 0.06 μM and 0.02 ± 0.10 μM, respectively. |
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| Keywords: | Cephalotaxus oliveri biflavonoid antioxidant activity |
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