| 气相色谱-质谱法快速测定牙膏中的二甘醇 |
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| 引用本文： | 金鹏飞,邹定,何笑荣,郭郁,孙春华,胡欣. 气相色谱-质谱法快速测定牙膏中的二甘醇[J]. 分析试验室, 2008, 27(11) |
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| 作者姓名： | 金鹏飞 邹定 何笑荣 郭郁 孙春华 胡欣 |
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| 作者单位： | 卫生部北京医院药学部,北京,100730;卫生部北京医院药学部,北京,100730;卫生部北京医院药学部,北京,100730;卫生部北京医院药学部,北京,100730;卫生部北京医院药学部,北京,100730;卫生部北京医院药学部,北京,100730 |
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| 摘 要： | 建立了气相色谱-质谱法（GC-MS）快速测定牙膏中的二甘醇的方法。牙膏样品经三氯甲烷提取后,应用气相色谱-质谱联用仪,以选择离子监测（SIM）模式对其中的二甘醇进行分析。二甘醇的线性范围为21.24-1062 mg/L,线性相关系数（r）为0.9995;检出限和定量限分别为2.0、5.0 mg/L;高、中、低3种浓度下的回收率在88.51%-101.6%之间,相对标准偏差（RSD）在1.6%-8.11%之间;仪器对二甘醇的响应在24 h内保持稳定。
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| 关 键 词： | 气相色谱-质谱联用仪 牙膏 二甘醇 |
Rapid determination of diethylene glycol in toothpastes by gas chromatography-mass spectrometry |
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| JIN Peng-fei,ZOU Ding,HE Xiao-rong,GUO Yu,SUN Chun-hua,HU Xin. Rapid determination of diethylene glycol in toothpastes by gas chromatography-mass spectrometry[J]. Chinese Journal of Analysis Laboratory, 2008, 27(11) |
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| Authors: | JIN Peng-fei ZOU Ding HE Xiao-rong GUO Yu SUN Chun-hua HU Xin |
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| Abstract: | A method for rapid determination of diethylene glycol in toothpastes by GC-MS was established.Toothpastes were extracted by chloroform and analyzed by GC-MS under selected ion monitoring(SIM) mode.In this method,the linear range of diethylene glycol was from 21.24 to 1062 mg/L with a correlative coefficient(r) of 0.9995;the limit of detection(LOD) and limit of quantitation(LOQ) were 2.0 and 5.0 mg/L,respectively;the average recoveries of high,middle,and low concentrations ranged from 88.51% to 101.6%,and th... |
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| Keywords: | Gas chromatography-mass spectrometry Toothpaste Diethylene glycol |
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