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Treatment of spasmodic dysphonia (laryngeal dystonia) with local injections of Botulinum toxin |
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| Authors: | Andrew Blitzer and Michael F. Brin |
| Affiliation: | 1Department of Otolaryngology, College of Physicians and Surgeons, Columbia-Presbyterian Medical Center, New York, New York, U.S.A. *Department of Neurology, College of Physicians and Surgeons, Columbia-Presbyterian Medical Center, New York, New York, U.S.A. †Dystonia Clinical Research Center, College of Physicians and Surgeons, Columbia-Presbyterian Medical Center, New York, New York, U.S.A. |
| Abstract: | In 1984 the authors performed the first laryngeal injection of Botulinum toxin for laryngeal dystonia via percutaneous, electromyographically guided technique. Since that time we have treated 450 patients with adductor spasmodic dysphonia, abductor spasmodic dysphonia, and adductor breathing dystonia. In general, the adductor patients received bilateral injections of 1.25 U to 3.75 U, obtaining greater than 90% of normal voice. The abductor patients received unilateral or staged bilateral injections of the posterior cricoarytenoid muscles with 0.6 to 3.75 U, obtaining 70% of normal function. We have found laryngeal injections of Botulinum toxin to be safe and effective therapy for the symptoms of laryngeal dystonia (spasmodic dysphonia). |
| Keywords: | Botulinum toxin Laryngeal dystonia |
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