Synthesis of a non-natural T-antigen containing glycosphingolipid |
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| Authors: | Cipolla L Meldal M |
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| Affiliation: | Department of Chemistry, Valby, Denmark. laura.cipolla@unimib.it |
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| Abstract: | A non natural glycosphingolipid containing the mucin derived, cancer associated disaccharide moiety Galbeta1-->3GalNAc, the T-antigen, alpha linked to a ceramide, has been synthesised via the protected disaccharide glycosyl trichloroacetimidate. The product has potential as a cancer vaccine. |
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