1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA;2. Program in International Child Health and Department of Pediatrics, Yale University School of Medicine, Child Health Research Center, 464 Congress Avenue, New Haven, CT 06520-8081, USA;3. Department of Immunology-Microbiology, Rush University Medical Center, Chicago, IL 60612, USA;4. NIH Chemical Genomics Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-3370, USA