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A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellular Function

Authors:	Christian Renicke Daniel Schuster Svetlana Usherenko Lars-Oliver Essen Christof Taxis

Affiliation:	1. Department of Biology/Genetics, Philipps-Universität Marburg, Karl-von-Frisch-Strasse 8, 35043 Marburg, Germany;2. Department of Chemistry and Biomedical Research Center, Philipps-Universität Marburg, Hans-Meerwein-Strasse, 35032 Marburg, Germany

Abstract:	Download : Download high-res image (288KB) Download : Download full-size image Highlights? Optogenetic tool to control the stability of soluble and membrane proteins ? Engineered using the LOV2 domain and a murine ornithine decarboxylase-like degron ? Creation of light-switchable, conditional mutants ? Graded response to very low blue light intensities allows yeast photography

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