1. State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
Abstract:
Highlights? The complete gougerotin biosynthetic gene cluster is cloned ? Heterologous production of gougerotin is accomplished in S. coelicolor M1146 ? Biosynthetic pathway is proposed based on bioinformatics, genetic, and chemical analyses ? Preliminary data support an uncommon enzymatic reaction for peptide bond formation