New ligands bearing chiral bioactive fragments |
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| Authors: | Khatyr A Ziessel R |
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| Institution: | Laboratoire de Chimie, d'Electronique et de Photonique Moléculaires, Associé au CNRS ESA-7008, Ecole de Chimie, Polymères, Matériaux de Strasbourg, 25 rue Becquerel, 67087 Strasbourg Cedex 02, France. |
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| Abstract: | see reaction]. Reliable and practical synthetic routes for the construction of hybrid molecules bearing both a chelating center and a useful biofunction are presented. They comprise the sequential cross-coupling reaction between ethynylated synthons with iodo-substituted L-tyrosine derivatives and provide access to various rationally designed chiral ligands. |
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