A catalytic-enantioselective entry to planar chiral pi-complexes: enantioselective methoxycarbonylation of 1,2-dichlorobenzene-Cr(CO)(3) |
| |
Authors: | Gotov B Schmalz H G |
| |
Affiliation: | Institut für Organische Chemie, Universit?t zu K?ln, Greinstrasse 4 D-50939 K?ln, Germany. |
| |
Abstract: | The palladium-catalyzed mono-methoxycarbonylation of 1,2-dichlorobenzene tricarbonylchromium(0) has been achieved with up to 95% ee in the presence of the chiral ferrocene ligand (R,S)-PPF-pyrrolidine. It was found that the enantioselectivity strongly depends on the reaction time (conversion). Obviously, the initial enantioselectivity is enhanced by a subsequent kinetic resolution connected to the formation of the bis-methoxycarbonylated byproduct. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|