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Anthelminthika,III Synthese und 13C-NMR-spektroskopische eigenschaften von (fluor- und iodanilino)ethentricarbonitrilen)
Affiliation:1. Department of Chemistry, McMaster University, Hamilton, Ontario L8S 4M1, Canada;2. Department of Inorganic Chemistry and Technology, Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia;1. Department of Chemistry, Faculty of Science, Ochanomizu University, 2-1-1, Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan;2. School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan;3. SANKEN, Osaka University, 8-1, Mihogaoka, Ibaraki-shi, Osaka 567-0047, Japan;4. Research Institute of Green Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka 432-8561, Japan
Abstract:The reaction of ethenetetracarbonitrile with the appropriate haloanilines leads to anilinoethenetricarbonitriles comprising halogen substitutions as follows: 2-fluoro-, 3-fluoro-, 4-fluoro-, 2,4-difluoro-, 3-iodo-, and 4-iodo. The new (fluoro- and iodoanilino)ethenetricarbonitriles are capable of exerting anthelminthic, fungicidal, and herbicidal activity. The structures of the reaction products were established spectroscopically (IR, 1H-NMR, 13C-NMR, and mass).
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