Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction |
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| Authors: | Zeng Qingbing Li Tao Cash Brandon Li Siqi Xie Fang Wang Qian |
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| Affiliation: | Department of Chemistry and Biochemistry and Nanocenter, University of South Carolina, Columbia, SC 29208, USA. |
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| Abstract: | Horse spleen apoferritin, the hollow protein shell derived from ferritin, a special biological nanoparticle, can be chemoselectively modified at the lysine residues, which affords a robust scaffold for further chemical reactions including Cu(i)-catalyzed azide-alkyne cycloaddition reaction and atom transfer radical polymerization reaction. |
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