Synthesis of alkylamine derivatives of 1-aryl-5-hydroxyindole |
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Authors: | A. N. Grinev V. I. Shvedov E. K. Panisheva |
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Affiliation: | (1) Ordzhonikidze All-Union Pharmaceutical Chemistry Research Institute, Moscow |
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Abstract: | Condensing substituted l-aryl-5-hydroxyindoles with bisdimethylaminomethane, or sodium-alcohol reduction of l-aryl-2-methyl-3-acetyl-5-methoxyindoles gives 4-dimethylaminomethyl and 3-alkylamino derivatives of 1-aryl-5-hydroxy (methoxy) indole, isolated as the hydrochlorides. |
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