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聚-N-异丙基丙烯酰胺的制备及应用进展
引用本文:吕菊波,纪秀翠,张亚会,徐慧.聚-N-异丙基丙烯酰胺的制备及应用进展[J].化学通报,2018,81(3):195-202.
作者姓名:吕菊波  纪秀翠  张亚会  徐慧
作者单位:鲁东大学化学与材料科学学院 烟台 264025,鲁东大学化学与材料科学学院 烟台 264025,鲁东大学化学与材料科学学院 烟台 264025,鲁东大学化学与材料科学学院 烟台 264025
摘    要:聚(N-异丙基丙烯酰胺)(PNIPAM)是一种温敏性高分子聚合物,在最低临界溶解温度(LCST)处会发生构象转变。对PNIPAM加以改性,可拓宽温敏性聚合物材料的研究领域,使其在药物负载运输、基因传递、化学分析和表面浸润性等领域发挥更大的应用价值。本文对PNIPAM的活性自由基聚合方法及其应用进展进行了综述,并展望了其发展前景。

关 键 词:聚(N-异丙基丙烯酰胺)  温敏性  最低临界溶解温度
收稿时间:2017/9/20 0:00:00
修稿时间:2017/12/3 0:00:00

Progress in Preparation and Application of Poly(N-isopropylacrylamide)
Lv Jubo,Ji Xiucui,Zhang Yahui and Xu Hui.Progress in Preparation and Application of Poly(N-isopropylacrylamide)[J].Chemistry,2018,81(3):195-202.
Authors:Lv Jubo  Ji Xiucui  Zhang Yahui and Xu Hui
Institution:School of Chemistry and Materials Science,Ludong University,School of Chemistry and Materials Science,Ludong University,School of Chemistry and Materials Science,Ludong University,School of Chemistry and Materials Science,Ludong University
Abstract:Poly(N-isopropylacrylamide) (PNIPAM) is one of the thermally responsive polymers, which has a lower critical solution temperature (LCST), and there is a phemomenon of the conformation variation around this temperature. The modification of PNIPAM play an important role in so many areas, such as the drug delibery, gene transfer and biochemical analysis and so on. In this article, the reaesrch progress of preparation and application of PNIPAM, and the prospects of this field were also put forward.
Keywords:Poly(N-isopropylacrylamide)  Thermally  responsive  Lower  critical solution  temperature
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