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NMR relaxation studies of GdDTPA in human serum albumin solution |
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| Affiliation: | 1. Department of Chemistry, Jamia Millia Islamia, New Delhi 110 025, India;2. Department of Chemistry, Al-Falah University, Dhauj, Faridabad 121 004, Haryana, India;1. School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu, 212013, China;2. Hainan Provincial Key Lab of Fine Chemistry, Hainan University, Haikou, Hainan, 570228, China;3. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106-7207, USA |
| Abstract: | The water relaxation enhancement behavior of GdDTPA in human serum albumin (HSA) solution has been studied The results indicate that GdDTPA can integrate noncovalently with HSAmainly in forms of (GdDTPA) HSA and (GdDTPA)2HSA for which the apparent equilibrium constants are 005 mM −1 and 002 mM −2respectively. |
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