Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts |
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Authors: | Vakulya Benedek Varga Szilárd Csámpai Antal Soós Tibor |
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Affiliation: | Institute of Biomolecular Chemistry, Chemical Research Center of Hungarian Academy of Sciences, Budapest. |
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Abstract: | Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields. |
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