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Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts
Authors:Vakulya Benedek  Varga Szilárd  Csámpai Antal  Soós Tibor
Affiliation:Institute of Biomolecular Chemistry, Chemical Research Center of Hungarian Academy of Sciences, Budapest.
Abstract:Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
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