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Reactions of 2,3-Dioxopyrrolo[2,1-a]isoquinolines with Ammonia and Aliphatic Amines
Authors:A G Mikhailovskii  N N Polygalova  T S Turova  G A Lobashova  M I Vahrin
Institution:(1) Perm State Pharmacological Academy, Perm, 614990, Russia
Abstract:2,3-Dioxopyrrolo2,1-a]isoquinolines, with either a tertiary amide substituent at position 1 or no substituent, react with ammonia and aliphatic amines with ring opening to form the corresponding enamino keto amides.
Keywords:amides of (3  3-dialkylisoquinolinidene-1)pyruvic and 2-oxobutandioic acids  ammonia  5  5-dialkyl-2  3-dioxopyrrolo[2  1-a]isoquinolines  methylamine  ethylamine
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