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Continuous production of inorganic magnetic nanocomposites for biomedical applications by laser pyrolysis |
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| Authors: | Sabino Veintemillas-Verdaguer Yann Leconte Rocío Costo Oscar Bomati-Miguel Brigitte Bouchet-Fabre M Puerto Morales Pierre Bonville Sandra Pérez-Rial Ignacio Rodriguez Nathalie Herlin-Boime |
| Institution: | 1. Instituto de Ciencia de Materiales de Madrid (CSIC), Sor Juana Inés de la Cruz 3, Cantoblanco, 28049 Madrid, Spain;2. SPAM/LFP Bat 522 (URA CEA-CNRS 2453), CEA Saclay, 91191 Gif/Yvette cedex, France;3. CEA, CE Saclay, Service de Physique de l′État Condensé, 91191 Gif-sur-Yvette, France;4. Unidad de RMN (UCM), Paseo Juan XXIII, 1, 28040 Madrid, Spain |
| Abstract: | Magnetic composites of Fe-based nanoparticles encapsulated in carbon/silica (C/SiO2@Fe) or carbon (C@Fe) matrices were prepared by laser-induced pyrolysis of aerosols. The powders were dispersed in aqueous solutions at pH 7 resulting in biocompatible colloidal dispersions with a high resistance to biodegradation. Structural and magnetic properties and the suitability of aqueous dispersions as contrast agent for MRI were analyzed. The results of these characterizations and the NMR relaxivity data are very encouraging for application of laser pyrolysis products in the field of living tissues. |
| Keywords: | Composites material Laser pyrolysis Magnetization curve Magnetic nanoparticle Colloid Contrast enhancement Magnetic resonance imaging Encapsulation |
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