| 多壁纳米碳管/二氧化硅复合膜中的联吡啶钌电化学发光法测定氧氟沙星的研究与应用 |
| |
| 引用本文： | 李利军,蓝苏梅,程昊,蔡卓,程龙军.多壁纳米碳管/二氧化硅复合膜中的联吡啶钌电化学发光法测定氧氟沙星的研究与应用[J].分析测试学报,2009,28(11). |
| |
| 作者姓名： | 李利军 蓝苏梅 程昊 蔡卓 程龙军 |
| |
| 作者单位： | 李利军,程昊(广西工学院,生物与化学工程系,广西,柳州,545006);蓝苏梅,蔡卓,程龙军(广西大学,化学化工学院,广西,南宁,530004) |
| |
| 基金项目： | 国家自然科学基金资助项目，广西科学基金资助项目 |
| |
| 摘 要： | 基于氧氟沙星对联吡啶钌(Ru(bpy)_3~(2+))电化学发光的增敏作用,建立了一种以多壁纳米碳管(MWCNTs)/二氧化硅-联吡啶钌复合物修饰的玻碳电极电化学发光检测氧氟沙星的新方法.利用溶胶-凝胶(sol-gel)固定化稳定的优点和纳米碳管的电催化作用,提高了传感器的电流响应.在最佳实验条件下,氧氟沙星浓度在4.0×10~(-6) ～1.0×10~(-4) mol/L范围内与相对发光强度呈线性关系(r~2=0.994 8),检出限(S/N=3)为2.0×10~(-6) mol/L.连续平行测定2.4×10~(-5) mol/L的氧氟沙星溶液 5次,发光强度的RSD为1.8%.
|
| 关 键 词： | 电致化学发光 联吡啶钌 多壁纳米碳管 溶胶-凝胶 |
Determination of Ofloxacin Hydrochloride Based on Multiwall Carbon-nanotube/SiO_2 Sol-Gel-Ru(bpy)_3~(2+) Using Electrochemiluminescence |
| |
| Abstract: | Based on the sensitization effect of ofloxacin on Ru(bpy)_3~(2+) electrochemiluminescence sys-tem, an electrochemiluminescence method for the determination of ofloxacin hydrochloride at multi-wall carbon nanotube/SiO_2 sol - gel - Ru( bpy)_3~(2+) composite film modified glass-carbon electrode was described. A highly-sensitive sensor was prepared based on multi-walled carbon nanotubes modified electrode conbined with SiO_2 sol - gel immobilization method. The fabrication procedure of the modi-fied electrode, and experiment conditions and electrochemical characteristics were studied in detail. Under the optimum condition, the calibration curve showed a good linearity over ofloxacin hydrochlo-ride concentration in the range of 4. 0 × 10~(-6) - 1.0 × 10~(-4) mol/L( r~2 = 0. 994 8 ) and the detection limit(S/N =3 ) was 2. 0 × 10~(-6) mol/L. The RSD for 5 times determination of 2.4 × 10~(-5) mol/L ofloxacin was 1. 8% . |
| |
| Keywords: | electrochemiluminescence tris ( 2 2'-bipyridyl) ruthenium ( Ⅱ ) multiwall carbon-nanotube sol - gel |
| 本文献已被 万方数据 等数据库收录！ |
|
